Phenazopyridine

Phenazopyridine is a medication used to relieve urinary pain, burning, urgency, and frequency associated with urinary tract infections. Phenazopyridine is not an antibiotic; it does not cure infections.

Phenazopyridine is both an over-the-counter and a prescription medication. The prescription form is used to relieve urinary tract pain, burning, irritation, and discomfort, as well as urgent and frequent urination caused by urinary tract infections, surgery, injury, or examination procedures. The over-the-counter form is used to relieve urinary tract pain, burning, irritation, and discomfort, as well as urgent and frequent urination caused by urinary tract infections.

Although the exact mechanism of action for phenazopyridine is unknown, it is a medication that has been used for many years to provide relief from urinary pain and discomfort.

This medication comes in tablet form and is taken three times a day after meals. Common side effects include red-orange or brown urine, headache, or upset stomach.  Phenazopyridine can also cause dizziness.  Do not drive or operate heavy machinery until you know how phenazopyridine affects you.

Phenazopyridine is a prescription medication used to relieve urinary tract pain, burning, irritation, and discomfort, as well as urgent and frequent urination caused by urinary tract infections, surgery, injury, or examination procedures.

Phenazopyridine is also available as an over-the-counter and is used to relieve urinary tract pain, burning, irritation, and discomfort, as well as urgent and frequent urination caused by urinary tract infections.

This medication may be prescribed for other uses.  Ask your doctor or pharmacist for more information.

Phenazopyridine may be found in some form under the following brand names:

• Azo Gantanol

• Azo Gantrisin

• Azo-Gesic

• Azo-Standard

• Azo-Standard Max Strength

• Azo-Truxazole

• Baridium

• Eridium

• Phenazo

• Prodium

• Pyridium

• Pyridium Plus

• Re-Azo

• Tija

• Uricalm

• Uristat

• Urobiotic

• Urodol

• Urogesic

• UTI Relief

• Viridium

Serious side effects have been reported with phenazopyridine.  See the phenazopyridine precautions section.  Common side effects of phenazopyridine include the following:

• Red-orange or brown colored urine (this is not harmful, but care should be taken to avoid staining clothing or other items)
• Headache
• Itching
• Stomach upset (taking with or after meals may reduce stomach upset)

This is not a complete list of phenazopyridine side effects.  Ask your doctor or pharmacist for more information.  Tell your doctor if you have any side effect that bothers you or that does not go away.  Call your doctor for medical advice about side effects.  You may report side effects to the FDA at 1-800-FDA-1088.

No drug interactions have been determined by the manufacturer.  However, you should tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.  Not all drug interactions are known or reported and new drug interactions are continually being reported.

Serious side effects have been reported with phenazopyridine including the following:

• Yellowing of skin or eyes
• Fever
• Confusion
• Skin discoloration (blue to bluish-purple)
• Shortness of breath
• Skin rash
• Sudden decrease in amount of urine
• Swelling of the face, fingers, feet, or legs

Phenazopyridine can cause dizziness.  Do not drive or operate heavy machinery until you know how phenazopyridine affects you.

Phenazopyridine should not be used for more than 2 days.

Phenazopyridine can interfere with laboratory tests, including urine tests for glucose (sugar) and ketones.

• If you have diabetes, you should use Clinitest rather than Tes-Tape or Clinistix to test your urine for sugar. Urine tests for ketones (Acetest and Ketostix) may give false results. Before you have any tests, tell the laboratory personnel and doctor that you take this medication.

Phenazopyridine can cause red-orange or brown colored urine. This is not harmful, but care should be taken to avoid staining clothing or other items.

Phenazopyridine stains contact lenses. Avoid wearing contact lenses while taking this medicine.

Phenazopyridine may cause teeth discoloration if the product has been broken or held in the mouth prior to swallowing.

Do not take phenazopyridine if you:

• Are allergic to phenazopyridine or to any of its ingredients
• Have renal impairment, including renal disease or renal failure

Medications can interact with certain foods.  In some cases, this may be harmful and your doctor may advise you to avoid certain foods.  In the case of phenazopyridine, there are no specific foods that you must exclude from your diet when receiving this medication.

Before taking phenazopyridine, tell your doctor about all of your medical conditions.  Especially tell your doctor if you:

• Are allergic to phenazopyridine or to any of its ingredients
• Have kidney disease
• Have sensitivities to glucose
• have any allergies to foods, preservatives or dyes
• Have a condition called Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency
• Are pregnant or breastfeeding

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy.  Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. 

Phenazopyridine falls into category B.  There are no well-done studies that have been done in humans with phenazopyridine.  In animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication.

Tell your doctor if you are breastfeeding or planning to breastfeed.  It is not known if phenazopyridine crosses into human milk.  Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with the use of this medication, a choice should be made whether to stop nursing or stop the use of this medication.  Your doctor and you will decide if the benefits outweigh the risk of using phenazopyridine.

Take phenazopyridine exactly as prescribed. 

Phenazopyridine comes in tablet form and is taken three times daily after meals and with a full glass of water.

When taken with an antibiotic for the treatment of a urinary tract infection, do not exceed 2 days. If symptoms persist, talk to your doctor.

Phenazopyridine may stain soft contact lenses and may be irreversible. Therefore, patients should not wear soft contact lenses while taking this medication.

If you miss a dose, take the missed dose as soon as you remember.  If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time.  Do not take two doses of phenazopyridine at the same time.

Prescription Form

Take this medication exactly as prescribed by your doctor.  Follow the directions on your prescription label carefully.

The recommended dose of phenazopyridine is 200 mg three times per day after meals.  The maximum daily dose is 600 mg.

Over-The- Counter Form

The recommended dose of phenazopyridine is two tablets three times per day after meals. However, be sure to follow the directions on the label carefully as there are many phenazopyridine products and the doses vary between each of them.

If you take too much phenazopyridine, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away. 

If phenazopyridine is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur.  However, if overdose is suspected, seek emergency medical attention.

• Store phenazopyridine at room temperature (between 59 to 86 degrees F). 
• Keep this and all medicines out of the reach of children.